Protecting brain and lungs: Precision medicine in PICU and NICU

  • October 27 - 29, 2022
  • Paris, France

Objectives

IPOKRaTES seminars provide high quality postgraduate education, which enable professionals to keep abreast of the most recent developments and offer participants the opportunity to discuss clinical problems or scientific issues personally with international experts. This seminar is designed to provide participants with a state-of-the art, comprehensive, and interdisciplinary approach to neurological and respiratory disease in critical neonates and children. Participants will learn about mechanisms- and etiology-driven management and new therapies in order to implement precisionmedicine approaches in the Pediatric and Neonatal Intensive Care Units. Lectures will focus on mechanisms of injury, multimodal monitoring in neonates and children at risk of lung and brain damage, neuroprotection, lung protection, and new treatment approaches and will be given ample chance to directly discuss with the international experts.

Faculty

  • M. Roberta Cilio
    Professor of Pediatric Neurology, University of Louvain, Pediatric and Neonatal Neurologist and Neurophysiologist, Cliniques Universitaires Saint-Luc, Brussels, Belgium
  • Daniele De Luca
    Full Professor of Neonatology, Chief of the Division of Pediatrics and Neonatal Critical Care, South Paris University Hospitals – Unité de Physiopathologie et Innovation Thérapeutique – INSERM U999, Université Paris Sud Saclay, Paris, France; President of the European Society for Pediatric and Neonatal Intensive Care (ESPNIC)
  • Frank van Bel
    Professor of Neonatology, University Medical Center Utrecht, The Netherlands
  • Olivier Danhaive
    Professor of Neonatology, Catholic University of Louvain, Chief of the Neonatal Intensive Care Unit, Cliniques Universitaires Saint-Luc, Brussels, Belgium
  • Barbara Schmidt
    Pediatrics and Senior Scholar in the Center for Clinical Epidemiology and Biostatistics at the University of Pennsylvania School of Medicine, USA
  • Nicola Specchio
    Director of Rare and Complex Epilepsies Center, Bambino Gesù Children’s Hospital and Research Institute, Rome, Italy
  • Rima Nabbout
    Professor of Pediatric Neurology, Director of the Rare Epilepsies Center of Reference, Paris, France
  • Karl Schettler
    Director of Pediatric and Neonatal Neuro-critical Care Program, Neonatology and Pediatric Intensive Care, Kinderkrankenhaus St. Marien gGmbH, Landshut, Germany
  • Robert Tasker
    Professor of Pediatric Anesthesia and Neuro-critical Care, Harvard Children Hospital, Boston, MA, USA
  • Virgilio Carnielli
    Full Professor of Neonatology, Polytechnical University of Marche, Division Chief NICU, “G.Salesi” Children Hospital, Ancona, Italy
  • Martin Kneyber
    Chief, Division of Critical Care Medicine Principal investigator, group leader „Optimizing paediatric mechanical ventilation“, Medical President-elect, European Society for Paediatric and Neonatal Intensive Care, Department of Paediatrics, Division of Paediatric Critical Care Medicine Beatrix Children‘s Hospital University Medical Center Groningen, Groningen, The Netherlands
  • Anton van Kaam
    Professor of Neonatology, Head Neonatal Intensive Care, Emma Children’s Hospital, Neonatal Intensive Care, Amsterdam, The Netherlands

Program

THU, October 27, 2022

08.00-08.30

Welcome and Introduction

D. De Luca & M. R. Cilio

08.30-09.30

Mechanisms of parenchymal lung injury in neonates

V. Carnielli

09.30-10.30

Mechanisms of parenchymal lung injury in children

M. Kneyber

10.30-11.00

Coffee break

11.00-12.00

Mechanisms of vascular lung disorders

O. Danhaive

12.00-13.00

Mechanisms of brain injury in neonates

F. van Bel

13.00-14.00

Lunch

14.00-15.00

Mechanisms of brain injury in critically ill children

R. Tasker

15.00-16.00

Cerebral monitoring in neonatal and pediatric critical care

K. Schettler

16.00-16.15

Coffee break

16.15-17.15

Seizures and status epilepticus in the NICU

M.R. Cilio

17.15-18:15

Brain on FIRES: Refractory and super-refractory status epilepticus in the PICU

R. Nabbout

FRI, OCTOBER 28, 2022

08.30-09.30

Precision medicine approach to neonatal and pediatric ARDS

D. De Luca

09:30-10:30

Point-of-care lung ultrasound to personalize respiratory care

D. De Luca

10.30-11.00

Coffee break

11.00-11.30

Monitoring during mechanical ventilation in neonates

A. van Kaam

11.30-12:00

Monitoring during mechanical ventilation in children

M. Kneyber

12.00-13.00

Precision medicine treatment for neurodegenerative pediatric diseases: The future is now

N. Specchio

13.00-14.00

Lunch

14:00-15.00

Strategies for neonatal neuro-protection

F.van Bel

15.00-16.00

Strategies for pediatric neuro-protection

R. Tasker

16.00-16.15

Coffee break

16:15-17.15

Personalized treatment of seizures in the neonate

M.R. Cilio

17.15-18.15

Personalized approach to children with traumatic brain injury

R. Tasker

SAT, OCTOBER 29, 2022

08.30-09.15

Lung protective ventilation in neonates

A. van Kaam

09.15-10:00

Lung protective ventilation in children

M. Kneyber

10.00-11.00

Biology – guided surfactant therapy in neonates and children

D. De Luca

11.00-11.30

Coffee break

11.30-12.30

Effect of cerebral stimulants of breathing physiology

B. Schmidt

12.30-13.30

Effect of whole-body hypothermia on the lung

D. De Luca

13.30-14.00

Open discussion and conclusions

Subject to change

Free Seats

Information

The number of participants is limited to 100

Participation Fees

Single person

  • before Sep 8, 2022
  • 450,00 Euro
  • after Sep 8, 2022
  • 480,00 Euro

 

Registration

Target Audience

Doctors, nurses and affiliates of university and non-university hospitals in the field of neonatal and pediatric intensive care, intensive care, pediatric and neonatal neurology and pulmonology, pediatric anesthesiology and neuro- and respiratory physiology

Local Organizer

Prof. Daniele DE LUCA (MD, PhD)
Service de Pédiatrie et Réanimation Néonatale, GHU Paris Sud, Hôpital “A. Béclère”
157 rue de la Porte de Trivaux, 92140 Clamart (Paris), France
Tel: +33 (0)145374837 - Fax: +33 (0)145374546 - Email: dm.deluca@icloud.com

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